The St. Jude Memphis Marathon Weekend is more than just a race—it’s a run with a purpose. As the premier fundraising event for St. Jude Children’s Research Hospital, this marathon, half marathon, 10K, and 5K bring together thousands of runners to support the hospital’s lifesaving mission. The course takes participants through downtown Memphis, past historic landmarks, and most powerfully, through the St. Jude campus, where patients and families cheer runners on. The race-day energy is unmatched, blending emotional inspiration with incredible community support.Memphis is a city rich in music, history, and Southern soul. After the race, explore Beale Street’s legendary blues scene, visit the National Civil Rights Museum, or refuel with world-famous Memphis barbecue. With Memphis International Airport providing easy access, it’s a meaningful and exciting destination race for runners of all backgrounds.Run for a Cause – Every step supports St. Jude Children’s Research Hospital, helping ensure families never receive a bill for treatment, travel, housing, or food.Powerful Race Experience – Running through the St. Jude campus, surrounded by cheering patients and families, makes this one of the most emotional and rewarding races in the country.Southern Hospitality & Music – From live bands on the course to the warm and welcoming community, Memphis delivers a race weekend filled with heart and soul.The route goes from downtown Memphis to the St. Jude campus.